Pharma Companies Are Running To Manufacture Covid-19 Active Tablet


An NHS nurse has a Coronavirus test kit while talking to reporters during a Coronavirus test drive at a parking lot on March 12, 2020 in Wolverhampton, England.
Figure: Christopher Furlong (Getty Images)

A new treatment for covid-19 may be around. Clinical trials of several people with the virus should be completed in the next few months, all taken as simple pills before delivery or as soon as the disease is confirmed.

Antibiotics, which are used to treat bacterial infections, and others very important a product that has been made. But we have fewer viruses available, for a number of reasons. For example, one of the drawbacks is that it is harder to make antiretroviral drugs than bacteria, because viruses take over our cells to reproduce (some bacteria do, but most of our problems do not). That is why the vaccine is our first line of action against viruses, which train the body’s immune system to detect the virus before it arrives, preventing the person from getting sick in the first place.

Just as the epidemic has allowed scientists to make advances in vaccine and development technology, there is hope that they too will improve the antiviral pipeline.

According to Kaiser Health News reports On Monday, there are at least three viruses being tested late in the US so far. The drug is being investigated as a drug of the past, which is given a few days after illness, while others are also considered to be a prescription drug for a person with covid-19 to prevent infection. And unlike viruses that have not been used yet, the virus is taken orally as a pill.

Monday, Pfizer (co-manufacturer of the first covid-19 vaccine in the US) he announced the start of a major experiment to test a competitor, called code-PF-07321332, as a prophylactic. Earlier this month, Merck and Ridgeback Biotherapeutics began Phase II / III testing of their molnupiravir drug. And earlier this summer, the companies Roche and Atea Pharmaceuticals began a major test of their drug called AT-527. Both companies want to release information from the trial over the next few months, while Merck wants permission to use the drug for emergency use within a year.

The pills are said to work by interfering with the coronavirus’s ability to replicate in a host cell, hopefully leading to a lower viral load and making it easier for the immune system to clear the infection. Ideally, these drugs would greatly reduce the length and severity of symptoms, preventing hospitalization and serious illness. And they may very well prevent an infection from taking hold altogether when taken as a prophylactic.

Of course, finding a highly effective treatment for covid-19 is easier said than done. The antiviral remdesivir, authorized for emergency use in the U.S., does seem to help hospitalized patients recover slightly faster, but there’s limited showing that it really helps prevent death. Some drugs, such as monoclonal antibodies, have shown many promises but are very expensive and need to be given through infusion, reducing their value and availability (further research showed that first aid with this can prevent serious illness).

Perhaps the most similar drug is Tamiflu, an FDA-approved drug that prevents or reduces the symptoms of the flu. Unfortunately, Tamiflu is very moderate above all, and some scientists have suggested that it should not be accepted in the first place.

The US has already agreed to buy more shares in the new covid-19 stock, provided it is eligible for approval or approval. In the best case scenario, they will be partners in vaccination against future waves of covid-19 or other coronaviruses in the future. But we need to wait for data from these clinical trials before we can hope.



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