This protein predicts the future of the brain after a traumatic injury


Neil Graham does not see Severe head injuries: “Car accidents, violence, beatings, shootings, stabbings-work, in fact,” says Graham, a sociologist at Imperial College London who lives in St. Petersburg. Mary’s Hospital nearby.

Doctors control the flow of blood, reduce any complications within the skull, and perhaps put the patient to overuse when he needs to rest and recover. Drawing can also help – to some extent. CT scans or MRIs detect pressure or scar tissue in gray, the outer part of the brain where neurons play a key role. But white scan is not a healthy thing. Injuries to the ax — nerve-like nerve roots that attach to other neurons — usually only appear on a very white surface, sometimes with little or no vision.

Axon damage is a major factor. Cognition is the function of motor vehicles where neurons cannot exchange messages. And when the white stuff takes the eagle, it falls It doesn’t just sit there, it just grows bigger, causing serious problems with thinking or walking. But doctors are not always aware of this damage. It is difficult to give survivors promises for the future. “Families and patients ask us early, ‘What will it be like six months or a year? When will I be back at work?

Sharp and Graham think they can find a solution in proteins, or residues, that are carried in human blood. He teamed up with trauma specialists across Europe in a study that tracked nearly 200 patients with head injuries for one year. The researchers looked at brain tests, plasma analysis, and pure fluid samples, tracking how five biomarkers correlated with the risk of injury — and human recovery. Results published in September in Science Interpretation Science, focused on one protein in particular: neurofilament light (NfL). NfL rates are rising weeks injured and can still climb after a year.

Plasma NfL I did not sell that axonal damage is, but it is a simple way to measure damage — and long-term follow-up — compared to advanced MRI technology.

“A brain injury, you think, is one event: Someone is injured and that’s it, they recover or they don’t,” says Richard Sylvester, a medical specialist at London Hospital National Neurology who did not participate in the study. “But we know there is a way to go beyond this.”

Electrical equipment is essential Symptoms, because they help doctors think about the disease instead of just having symptoms. The symptoms are usually mild, depending on the patient’s experience. He tells you what the injury is, not what the actual injury was. Biomarkers, however, can act as water receipts that point to other events, such as shaving axons.

For example, when a patient gives a vague diagnosis such as chest pain, for example, cardiologists can test biomarkers like troponins and use this information to differentiate heart disease or something less serious, such as gas or muscle. “You drill on the floor. You get a certain disease,” Graham says.



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